
Xylazine Portal
As xylazine continues to ravage the United States, we are doing everything we can to keep our community informed. This page is dedicated exclusively to xylazine information and updates.
From CCODP
What Is Xylazine?
Xylazine—also known as “tranq”—has entered California’s drug market. What do you need to know?

The Xyla-Zine
CCODP has created a simple foldable zine to inform the public about what xylazine is and how to stay safe.

From Our Partners
National Harm Reduction Coalition Xylazine Fact Sheet
Xylazine—also known as “tranq”—has entered California’s drug market. What do you need to know?

California Public Health Department Xylazine Fact Sheet
CCODP has created a simple foldable zine to inform the public about what xylazine is and how to stay safe.

From the California Department of Public Health
Xylazine in the Illicit Drug Supply and Patient Best Practices
This All Facilities Letter (AFL) from CDPH notifies all facilities of the veterinary sedative xylazine emerging in the United States (U.S.) illicit drug supply, predominantly with fentanyl use. Despite its low presence in California, levels could increase. Facilities should be prepared to support patients who have been exposed to xylazine.
CDPH Warns Californians About the Dangers of Xylazine
In response to the increase of xylazine in the illegal drug supply in the U.S., the California Department of Public Health (CDPH) has issued a letter to healthcare facilities and providers outlining the risks and warning signs of exposure, as well as patient care recommendations.
About Xylazine
Xylazine is an animal tranquilizer which is reaching the US illicit drug supply (“on the street”) where it is known as “tranq” or “tranq dope.” Xylazine has been linked to an increasing number of overdose deaths nationwide. Some people who use drugs are taking xylazine knowingly in combination with other drugs, especially fentanyl. Other people who use drugs are not aware their drug supply contains xylazine at all.
